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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
19.09
Human Site:
Y1245
Identified Species:
35
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
Y1245
A
S
L
N
F
L
D
Y
I
S
S
N
N
R
Q
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
D1221
F
S
P
F
G
A
A
D
Q
D
P
F
P
K
S
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
Y1245
A
S
L
S
F
L
D
Y
I
S
S
N
N
R
Q
Dog
Lupus familis
XP_534693
2280
250152
Y1314
A
S
L
S
F
L
D
Y
I
S
S
N
S
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
Y1244
A
S
L
S
F
L
D
Y
I
S
S
A
N
R
H
Rat
Rattus norvegicus
NP_001101807
1374
149708
T444
A
D
N
N
D
Y
W
T
E
C
V
N
A
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
D1204
F
S
P
F
G
A
A
D
Q
D
P
A
P
R
I
Chicken
Gallus gallus
XP_415317
2195
241321
Y1224
T
S
L
S
C
L
D
Y
M
S
S
N
N
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
V1156
A
S
L
K
R
G
T
V
L
E
E
Q
V
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
V1650
L
E
Q
L
G
H
A
V
F
D
L
L
L
D
Q
Honey Bee
Apis mellifera
XP_393643
1982
216109
L1052
P
P
S
V
L
E
L
L
R
E
Q
C
L
I
I
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
L1724
S
H
V
D
A
L
E
L
L
M
L
G
N
S
V
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
T197
Q
C
N
S
P
Y
A
T
L
A
R
L
A
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
6.6
93.3
86.6
N.A.
80
20
N.A.
13.3
73.3
N.A.
20
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
26.6
N.A.
13.3
86.6
N.A.
26.6
N.A.
6.6
0
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
8
16
31
0
0
8
0
16
16
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
8
0
8
0
0
8
% C
% Asp:
0
8
0
8
8
0
39
16
0
24
0
0
0
8
8
% D
% Glu:
0
8
0
0
0
8
8
0
8
16
8
0
0
0
8
% E
% Phe:
16
0
0
16
31
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
24
8
0
0
0
0
0
8
0
8
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
31
0
0
0
0
8
16
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
47
8
8
47
8
16
24
0
16
16
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
16
16
0
0
0
0
0
0
0
39
39
0
0
% N
% Pro:
8
8
16
0
8
0
0
0
0
0
16
0
16
8
0
% P
% Gln:
8
0
8
0
0
0
0
0
16
0
8
8
0
0
39
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
8
0
0
47
0
% R
% Ser:
8
62
8
39
0
0
0
0
0
39
39
0
8
8
8
% S
% Thr:
8
0
0
0
0
0
8
16
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
16
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _